Quality Unit(s) with Peroxisome

Side effects and complications in the use of drugs: diarrhea, rash, alopecia and palmar-pidoshvova erytrodyzesteziya (palmar skin pidoshvovyy-c-m), anorexia, headache, hypertension, hot flashes, diarrhea, nausea, vomiting, constipation, rash, alopecia, pruritus, erythema, dry skin, peeling skin, arthralgia, pain in extremities, fatigue, asthenia. Method of production of drugs: Table., Film-coated, 200 mg. Dosing and Administration of drug: internal, 250 mg 1 g / day, regardless of the meal. Indications for use drugs: widespread renal cell carcinoma, hepatocellular carcinoma. Side effects and complications in the use of drugs: rash, diarrhea I and II severity, not requiring the wallaby the average time before a rash - 8 days before the beginning of diarrhea - 12 days, anorexia, diarrhea, vomiting, stomatitis, dyspepsia, abdominal pain may also occur gastrointestinal bleeding liver dysfunction (including increased ALT, AST, bilirubin), which mostly disappear quickly, light or moderate severity, or associated with liver metastases, conjunctivitis, dry keratoconjunctivitis, keratitis, corneal ulcers, cough, dyspnea, nasal bleeding, Interstitial lung disease (interstitial pneumonia, obliterative bronchiolitis, pulmonary wallaby respiratory distress g-c-m and infiltration of the wallaby including cases with fatal outcome), headache, neuropathy, depression, rash, alopecia, dry Creatinine Clearance itching, fever, fatigue, severe Foreign Body Contraindications to the use of drugs: hypersensitivity to the drug. Pharmacotherapeutic group: L01XE - inhibitor Upper Respiratory Quadrant protein-tyrosine kinase.